Hutch News

Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer

Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer

Researchers use CRISPR-Cas9 gene-editing tool on tumor cells grown in mice to better model how tumors that initially respond to chemotherapy become resistant
Hutch NewsMay 08, 2025
When antibodies become anti-body

When antibodies become anti-body

From the Houghton and Lampe labs, Clinical Research and Public Health Sciences Divisions
Science SpotlightFebruary 20, 2023
CD133 auto-antibodies shine a light on early-stage small cell lung cancer

CD133 auto-antibodies shine a light on early-stage small cell lung cancer

From the Dr. Paul D Lampe, Dr. Christopher Li, and Dr. A McGarry Houghton Labs, Cancer Epidemiology, Prevention and Control and Cancer Immunology Programs, Cancer Consortium.
Science SpotlightAugust 15, 2022
New insights into drug resistance in small cell lung cancer

New insights into drug resistance in small cell lung cancer

Scientists discover a single gene’s outsized role in drug resistance — and use its vulnerability to re-sensitize tumors to chemotherapy in preclinical models
Hutch NewsAugust 20, 2020
Q&A: A new focus on small cell lung cancer

Q&A: A new focus on small cell lung cancer

Dr. David MacPherson discusses the state of small cell lung cancer research, how his lab is tackling this deadly disease, and what makes him excited for the future
Hutch NewsFebruary 07, 2019
Path to a targeted treatment for small-cell lung cancer?

Path to a targeted treatment for small-cell lung cancer?

Researchers show how common mutation in SCLC makes mouse tumors more vulnerable to certain cancer drugs
Hutch NewsSeptember 04, 2018